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What is Renuva and How It Works

Renuva has taken the aesthetic industry by storm by essentially creating it’s own space in the market. Renuva is a non-surgical injectable made from processed donated human adipose (fat) tissue, marketed by MTF Biologics as an “off‑the‑shelf alternative” to fat grafting. It sounds scary but the donated tissue goes through a sterility process to avoid an immune reaction. The extracellular matric is extracted from the tissue. Once injected, the extracellular matrix creates a scaffold that your own fat cells populate over 3 to 6 months, leading to restored volume. Below we’ll discuss the use of renuva, its typical costs, who’s a good candidate, and more!

What It’s Used For

What’s amazing about Renuva is that it treats volume loss and contour issues in areas where fat naturally exists. Some common uses include:

  • Facial hollows (temples, cheeks, prejowl areas)
  • lack of fullness to neck
  • Backs of hands
  • Depressed scars and dimples (e.g., cellulite or post-liposuction irregularities)
  • Subtle breast assymetry and chest lines

Unlike Hyaluronic acid fillers or fat transfer, Renuva doesn’t sculpt bony structures or treat lips/tear troughs, but it’s great at natural‐looking volume restoration over time

What Renuva Is Made Of

Renuva consists of a human adipose-derived extracellular matrix rich in collagen, proteins, and growth factors, but without live cells or DNA, minimizing immune response. It meets FDA and AATB standards for safety and biocompatibility. In order to prevent cross-contamination, the cell content is removed from the donor tissue and all that’s left is the matrix which contains the contents that surround the fat cell like proteins, collagen and hyaluronic acid. Once the matrix is injected, the body recognizes the components and the fat cells go into the matrix, establishing a blood supply and stimulating the body to create its own fat cell.

Typical Cost of Treatment

  • Average cost per syringe: $1,500–$2,843
  • Total treatment sessions range from 1 to 3, depending on target area and desired volume

Of course, patients in major cities may pay more, and price may vary depending on injector and expertise.

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Who Is a Good Candidate

Ideal candidates:

  • People with mild to moderate volume loss, especially in natural fat pad areas
  • Those facing filler fatigue or “Ozempic face” and seeking a more natural results
  • Individuals without enough body fat for autologous grafting, but who want long-term, natural‑feeling volume

Who Might Not Be Suitable

Renuva is not meant for surgical contouring, major volume deficits, or volumizing lips, tear troughs, or muscle-rich areas.

Patients with ongoing weight loss or active use of fat-loss medications may not see optimal outcomes. Alternatives like fillers, collagen stimulators (e.g., Sculptra), or fat grafts may be more appropriate for those goals.

Additionally, because Renuva is non-reversible and not enzyme-dissolvable, correct placement is crucial. There is also a rare risk of allergic reaction or vascular complications.


Safety and Longevity

Renuva is regulated as a Human Cell, Tissue and Cellular and Tissue-Based Product (HCT/P) a different category than dermal fillers. Clinical reports show volume retention can last up to 8–10+ years, though most studies track outcomes for only 6 months. Bruising and swelling are common, but downtime is typically minimal.

Should You Do it?

If you’re a patient or aesthetic professional exploring treatments, Renuva offers a regenerative, long-term solution for mild to moderate volume loss without surgery. It’s ideal for those seeking natural-looking, durable results. Its safety track record, long lifespan, and scaffold-based mechanism make it a possible alternative to fillers or fat grafts. Just be sure you have realistic expectations and you’re treated by a trained provider.

Also Read: The Remarkable Benefits Of Temple Filler In Aesthetic Treatments

References

https://www.allure.com/story/renuva-regenerative-injectable

https://www.rejuvemedicalspa.com/blog-1/tag/How%2Bmuch%2Bdoes%2BRenuva%2Bcost%3F

https://www.mtfbiologics.org/our-products/detail/renuva

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